Penciclovir
A to Z Drug Facts
| (pen-SICK-low-vihr) |
| Denavir |
| Class: Topical anti-infective/Antiviral |
Action Selectively inhibits herpes viral DNA synthesis and replication.
Indications Treatment of recurrent herpes labialis (cold sores) in adults.
Contraindications Standard considerations.
Route/Dosage
ADULTS: Topical Apply to lesions q 2 hr while awake for 4 days. Start treatment as early as possible, during the prodrome or when lesions first appear.
Interactions None well documented.
Lab Test Interferences None well documented.
Adverse Reactions
DERM: Application site reaction.
Precautions
Pregnancy: Category B. Lactation: Undetermined. Children: Safety and efficacy not established. Elderly: Side effect profile similar to younger patients.
| PATIENT CARE CONSIDERATIONS |
|
Administration/Storage
- Available as a topical cream.
- Wash hands before and after application.
- Apply small amount using finger cot or glove every 2 hours directly on lesion. Avoid application in or near eyes or mucous membranes.
- Store at room temperature (59° to 86°F). Do not freeze.
Assessment/Interventions
- Assess lesions prior to and daily during therapy.
- Report any local reaction to physician.
Patient/Family Education
- Obtain patient history, including drug history and any known allergies.
- Instruct patient to begin treatment as soon as possible, during the prodrome, or as soon as lesions appear.
- Advise patient to apply the medication exactly as directed and to only apply to lesions on the face and lips.
- Advise patient to avoid applying cream to mucous membranes, within or near eyes.
- Advise patient to wash hands before and after applying cream.
- Advise patient to discontinue use and notify physician if local irritation develops.
- Advise the patient that the use of additional otc creams or ointments may delay the healing process or even spread the disease.
- Instruct the patient to notify the physician if the symptoms do not improve in 7 days of topical therapy.
- Instruct the patient to apply sufficient ointment to cover all lesions every 2 hours while awake.
- Advise the patient to use a finger cot or glove when applying the ointment to prevent the spread of virus.
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Copyright © 2003 Facts and Comparisons
David S. Tatro
A to Z Drug Facts